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Wednesday 25 April 2012

Dengue Fever Asian Mosquito Could Invade UK

Asian Tiger Mosquito

The mosquito can carry dengue and chikungunya viruses

 

A mosquito that spreads tropical diseases including dengue fever may be poised to invade the UK because of climate change.

The Asian tiger mosquito has already been reported in France and Belgium and could be migrating north as winters become warmer and wetter.

Scientists have urged "wide surveillance" for the biting insect across countries of central and northern Europe, including the UK.

The mosquito can carry dengue and chikungunya viruses, both of which cause high fevers. The infections usually occur in tropical regions of Africa, Asia and South America.

Scientists led by Dr Samantha Martin, from the University of Liverpool, used climate models to predict how changing conditions might affect Asian tiger mosquito distribution.

They wrote in the Journal of the Royal Society Interface: "Mosquito climate suitability has significantly increased over the southern UK, northern France, the Benelux, parts of Germany, Italy, Sicily and the Balkan countries."

The research shows that parts of the UK could become hot-spots of Asian tiger mosquito activity between 2030 and 2050.

The mosquito has been introduced into Europe from Asia via goods shipments, mainly used tyres and bamboo.

Climate change is now shifting conditions suitable for the insect from southern Europe to central north-western areas.

The mosquito could survive in water butts and vases, and may find winter protection in greenhouses, said the researchers.

Tuesday 24 April 2012

Opiates Killed 8 Americans In Afghanistan, Army Records Show

Eight American soldiers died of overdoses involving heroin, morphine or other opiates during deployments in Afghanistan in 2010 and 2011, according to U.S. Army investigative reports. The overdoses were revealed in documents detailing how the Army investigated a total of 56 soldiers, including the eight who fell victim to overdoses, on suspicion of possessing, using or distributing heroin and other opiates. At the same time, heroin use apparently is on the rise in the Army overall, as military statistics show that the number of soldiers testing positive for heroin has grown from 10 instances in fiscal year 2002 to 116 in fiscal year 2010. Army officials didn't respond to repeated requests for comment on Saturday. But records from the service's Criminal Investigation Command, obtained by the conservative legal group Judicial Watch, provided glimpses into how soldiers bought drugs from Afghan juveniles, an Afghan interpreter and in one case, an employee of a Defense Department contractor, who was eventually fired. The drug use is occurring in a country that is estimated to supply more than 90% of the world's opium, and the Taliban insurgency is believed to be stockpiling the drug to finance their activities, according to a 2009 U.N. study. While the records show some soldiers using heroin, much of the opiate abuse by U.S. soldiers in Afghanistan involves prescription drugs such Percocet, the Army documents show. Judicial Watch obtained the documents under the Freedom of Information of Act and provided them to CNN. Spokesman Col. Gary Kolb of the International Security Assistance Force, the NATO-led command in Afghanistan, verified the documents to CNN on Saturday. One fatal overdose occurred in June 2010 at Forward Operating Base Blessing, after a soldier asked another soldier to buy black tar opium from a local Afghan outside the base's entry control point. The first soldier died after consuming the opium like chewing tobacco and smoking pieces of it in a cigarette, the documents show. The reports even show soldier lingo for the drug -- calling it "Afghani dip" in one case where three soldiers were accused of using the opiate, the Army investigative reports show. The United States has 89,000 troops in Afghanistan. The U.S. death toll since the September 11, 2001, attacks that triggered the war has risen to more than 1,850, including 82 this year, according to the U.S. Department of Defense and U.S. Central Command. Tom Fitton, president of Judicial Watch, said his group was interested in soldiers' drug use partly because the risk was present during the Vietnam War. "You never want to see news of soldiers dying of drug use in Afghanistan," Fitton said. "Our concern is, will the military treat this as the problem that it is, and are the families of the soldiers aware of the added risk in this drug-infested country? "There is a dotted line between the uses. Prescription abuse can easily veer into heroin drug use," Fitton added. "Afghanistan is the capital of this opiate production and the temptation is great there and the opportunity for drug use all the more." The group is concerned that "there hasn't been enough public discussion, and we would encourage the leadership to discuss or talk about this issue more openly," Fitton said. In one case, a soldier bought heroin and the anti-anxiety drug Xanax from five "local national juveniles at multiple locations on Camp Phoenix, Afghanistan, and consumed them," one report states. Soldiers also distributed heroin, Percocet and other drugs among themselves, according to the reports. Another soldier fatally overdosed in December 2010 after taking several drugs, including morphine and codeine, though the drugs were not prescribed for him, the Army documents show. One female soldier broke into the Brigade Medical Supply Office at Forward Operating Base Shank and stole expired prescription narcotics including morphine, Percocet, Valium, fentanyl and lorazepam, the documents show. The investigative reports show soldiers using other drugs, including steroids and marijuana, and even hashish that was sold to U.S. servicemen by the Afghan National Army and Afghan National Police personnel, the reports state.

Monday 23 April 2012

exploding the common myths about which foods are good for us

Myth: Salt in your diet causes high blood pressure

In the 1940s, Walter Kempner, a researcher at Duke University, North Carolina, became famous for using salt restriction to treat people with high blood pressure. Later, studies confirmed that reducing salt could help reduce hypertension. But you don't have to avoid salt entirely, says Sara Stanner, of the Nutrition Society. "Adults need a small amount of sodium in their diet to maintain the body's fluid balance."

Average salt intakes have come down in recent years, mainly due to product reformulation. But it's still the case that many of us consume too much salt – around 9g a day instead of the maximum recommended dose of 6g per day – around 75 per cent of which is in processed foods such as soups, sauces, sandwiches and processed meat.

"People often think it's really bad to add salt into cooking or on to your plate, but that forms no more than 10 per cent of your total intake," says Stanner. "So you can get people who never have salt at their table, but have a very high salt intake, while others put salt on most meals, but have a lower intake."

Myth: Carbohydrates are bad for you

"Carbohydrate-rich foods are an ideal source of energy. They can also provide a lot of fibre and nutrients," says Sara Stanner. "Potatoes, for instance, are one of the best sources of vitamin C, yet potato consumption in the UK has fallen considerably."

One of the main reasons carbohydrates have fallen out of favour is that they are perceived to be fattening. "Foods high in carbohydrates have had a rough time in the past few years, thanks to the success of low-carb diets, such as the Atkins diet," explains Juliette Kellow.

"But there's no proof that carb-rich foods are more likely to make us gain weight than any other food. Ultimately, it's an excess of calories that makes us pile on the pounds – and it really doesn't matter where those extra calories come from. More often than not, it's the fat we add to carbs that boosts the calorie content, such as butter on toast, creamy sauces with pasta and frying potatoes to make chips."

Myth: Dairy products are fattening and unhealthy

In a study by the Curtin University of Technology in Perth, Australia, slimmers on low- calorie diets which included cheese, yoghurt and milk lost more weight than those on low-dairy diets. Those on the diet including dairy also had the least stomach fat, lower blood pressure and a significantly better chance of avoiding heart disease and diabetes.

Dairy products are packed with essential nutrients that help keep us healthy, says Juliette Kellow. "As well as being good sources of protein, zinc and some B vitamins, dairy products are packed with calcium, a mineral that helps to build strong, healthy bones – and the stronger the bones are, the less likely you'll be to suffer from osteoporosis in later life."

There are loads of low-fat versions of dairy, such as skimmed or semi-skimmed milk, low-fat yoghurts and reduced-fat cheeses, she says – and low-fat versions don't mean less calcium. "Skimmed and semi-skimmed milk actually contain slightly more calcium than full-fat milk."

Myth: Red meat is bad for you

Publishing what it called "the most authoritative ever report of bowel cancer risk" last year, the World Cancer Research Fund recommended that people limit their intake of red meat to 500g a week, or just over a pound in weight. The net result of such studies is always the same – people panic.

But 500g is roughly the equivalent of five or six medium portions of roast beef, lamb or pork. "Red meat is a valuable source of minerals and vitamins, particularly iron, and we know that large numbers of women have such low intakes of this nutrient that they're at risk of anaemia. There's no need for people to think, 'I should be eating fish' when they have a steak,' provided they eat it in moderation," says Sarah Schenker.

Another myth about red meat is that it's high in fat, says Juliette Kellow, dietitian and advisor to Weight Loss Resources. "Thanks to modern breeding programmes and new trimming techniques, red meat is now leaner than ever.

Processed meat of all kinds, however, should be avoided.

Myth: Fresh is always better than frozen

Frozen fruit and vegetables can be more healthy than fresh. "Research shows that freezing vegetables such as peas as soon as they're picked – when they are at their nutritional peak – means they retain higher levels of vitamins, particularly vitamin C," says Sarah Schenker. "Once frozen, the deterioration process stops, locking in goodness. The fresh variety often travel long distances and sit on grocery shelves and along the way, heat, air, water and time can lead to a significant loss of nutrients."

Frozen or canned fruits and vegetables can also be as nutritious as fresh ones, if not more so. Again, they are often packaged within hours of being picked, retaining their nutritional value. "Always check salt and sugar levels though by comparing labels," says Sarah Schenker, of the British Dietitic Association. Even dried fruit can be healthier than fresh. "When you eat dried fruit you usually eat more than the fresh equivalent – for instance six dried apricots instead of three fresh ones. This is more calorific but you get a bigger amount of nutrients," says Schenker.

Myth: Soy eases menopausal problems

For years, the fact that Asian women have fewer menopausal symptoms has been attributed to high levels of soy in their diet. Soy products such as tofu contain natural plant oestrogens and there have been increasing claims that these might help women going through the menopause whose own oestrogen levels are dwindling.

But a University of Miami study has found that soy does nothing to abate hot flushes and bone-density loss. In fact, the women given soy appeared to experience more hot flushes than those given a placebo.

Experts including Dr Malcolm Whitehead, a menopause expert at King's College Hospital in London, aren't surprised. "In my clinical experience, women say this doesn't work for them," he says, adding that HRT is a safe and effective treatment for most women.

Others point to previous studies showing that soy can work, but the British Dietetic Association's Sarah Schenker, says, "This research has always been weak. People got excited about those early small studies, but the more research that was done, the more doubts appeared."

Myth: Brown bread is better for you than white

A darker loaf of bread does not necessarily mean it's made with whole grains – it could simply contain caramel colouring or such a small amount of whole wheat that its nutritional benefits are no different to white bread. "The real health benefits come from eating wholemeal bread instead of white," says Sarah Schenker.

Wholemeal is made from flour containing all the goodness of wheat grains. The outer husk has not been removed, so the resulting bread is much richer in fibre, protein and vitamins B1, B2, niacin, B6, folic acid and biotin. Brown bread, in contrast, is made from finely milled wheat, from which the bran has been extracted.

Look for the words "whole grain" or "100% whole wheat" on packaging and ensure the first ingredient listed is whole wheat, oats, whole rye, whole grain corn, barley, quinoa, buckwheat or brown rice. Seeded bread is even better, since it contains even more vitamins, minerals and healthy fats.

Myth: Everyone needs a lot of protein

Protein is essential for growth and development, but experts agree that most people eat far too much of it. "The Department of Health recommends that protein should make up around 10-15 per cent of your daily diet – that's around 55g for men and 45g for women," dietitian Azmina Govindji says. "Yet, according to the British Nutrition Foundation, men are probably munching their way through an average of 88g and women around 64g."

So what's fuelling this notion that we need so much? "Some diets, such as the Atkins diet, advocate speedy weight loss on cutting the carbs and piling on the proteins", Govindji says.

Another contributory factor is that in the past, it was believed nobody could eat too much protein. In the early 1900s, people were told to eat well over 100g a day and in the 1950s, health-conscious people were encouraged to boost their protein intake. But high protein can put a strain on liver and kidneys and other bodily systems.

Friday 20 April 2012

What cannabis actually does to your brain

Archaeologists recently found a 2,700-year-old pot stash, so we know humans have been smoking weed for thousands of years. But it was only about 20 years ago that neuroscientists began to understand how it affects our brains.

Scientists have known for a while that the active ingredient in cannabis was a chemical called delta-9-tetrahydrocannabinol, or THC for short. Ingesting or smoking THC has a wide range of effects, from the psychoactive "getting high" to the physiological relief of pain and swelling. It also acts as both a stimulant and depressant. How could one substance do all that?

What cannabis actually does to your brainMeet the cannabinoid receptor

In the 1980s and 90s, researchers identified cannabinoid receptors, long, ropy proteins that weave themselves into the surfaces of our cells and process THC. They also process other chemicals, many of them naturally occurring in our bodies. Once we'd discovered these receptors, we knew exactly where THC was being processed in our bodies and brains, as well as what physical systems it was affecting. Scattered throughout the body, cannabinoid receptors come in two varieties, called CB1 and CB2 - most of your CB1 receptors are in your brain, and are responsible for that "high" feeling when you smoke pot. CB2 receptors, often associated with the immune system, are found all over the body. THC interacts with both, which is why the drug gives you the giggles and also (when interacting with the immune system) reduces swelling and pain.

 

Cannabinoid receptors evolved in sea squirts about 500 million years ago; humans and many other creatures inherited ours from a distant ancestor we share with these simple sea creatures. THC binds to receptors in animals as well as humans, with similar effects.

Tasty, tasty, tasty

Cannabis notoriously makes people hungry - even cancer patients who had lost all desire to eat.One study showed that cancer patients who thought food smelled and tasted awful suddenly regained an ability to appreciate food odors after ingesting a THC compound. There are CB1 receptors in your hypothalamus, a part of your brain known to regulate appetite, and your body's own cannabinoids usually send the "I'm hungry" message to them. But when you ingest THC, you artificially boost the amount of cannabinoids sending that message to your hypothalamus, which is why you get the munchies.

Understanding this process has actually led to a new body of research into safe diet drugs that would block those cannabinoid receptors. That way, your hypothalamus wouldn't receive signals from your body telling it to eat, and would reduce hunger cravings in dieters.

What you're forgetting

What's happening in your brain when smoking pot makes you forget what you're saying in the middle of saying it? According to the book Marijuana and Medicine (National Academies Press):

One of the primary effects of marijuana in humans is disruption of short-term memory. That is consistent with the abundance of CB1 receptors in the hippocampus, the brain region most closely associated with memory. The effects of THC resemble a temporary hippocampal lesion.

That's right - smoking a joint creates the effect of temporary brain damage.

What happens is that THC shuts down a lot of the normal neuroprocessing that goes on in your hippocampus, slowing down the memory process. So memories while stoned are often jumpy, as if parts are missing. That's because parts literally are missing: Basically you are saving a lot less information to your memory. It's not that you've quickly forgotten what's happened. You never remembered it at all.

What cannabis actually does to your brainA bit of the old timey wimey

Cannabis also distorts your sense of time. THC affects your brain's dopamine system, creating a stimulant effect. People who are stoned often report feeling excited, anxious, or energetic as a result. Like other stimulants, this affects people's sense of time. Things seem to pass quickly because the brain's clock is sped up. At the same time, as we discussed earlier (if you can remember), the drug slows down your ability to remember things. That's because it interferes with the brain's acetylcholine system, which is part of what helps you store those memories in your hippocampus. You can see that system's pathway through the brain in red in the illustration at left.

In an article io9 published last year about the neuroscience of time, we noted:

The interesting thing about smoking pot is that marijuana is one of those rare drugs that seems to interact with both the dopamine and the acetylcholine system, speeding up the former and slowing down the latter. That's why when you get stoned, your heart races but your memory sucks.

It's almost as if time is speeding up and slowing down at the same time.

Addiction and medicine

Some experts call cannabis a public health menace that's addictive and destroys lives by robbing people of ambition. Other experts call it a cure for everything from insomnia to glaucoma, and advocate its use as a medicine. The former want it to be illegal; the latter want it prescribed by doctors. Still other groups think it should be treated like other intoxicants such as alcohol and coffee - bad if you become dependent on it, but useful and just plain fun in other situations.

What's the truth? Scientists have proven that cannabis does have medical usefulness, and the more we learn the more intriguing these discoveries become. Since the early 1980s, medical researchers have published about how cannabis relieves pressure in the eye, thus easing the symptoms of glaucoma, a disease that causes blindness. THC is also "neuroprotective," meaning in essence that it prevents brain damage. Some studies have suggested that cannabis could mitigate the effects of Alzheimer's for this reason.

At the same time, we know that THC interferes with memory, and it's still uncertain what kinds of long-term effects the drug could have on memory functioning. No one has been able to prove definitively that it does or does not erode memory strength over time. Obviously, smoking it could cause lung damage. And, like the legal intoxicant alcohol, cannabis can become addictive.

Should cannabis be illegal, while alcohol flows? Unfortunately that's not the kind of question that science can answer. Let's leave the moral questions to courts, policymakers and shamans. I'll be off to the side, smoking a joint, thinking about my acetylcholine system and the many uses of the hippocampus.

Friday 13 April 2012

Surf Air: Can an all-you-can-fly airline possibly work?

 

SURF AIR, a Californian start-up, has a novel business model: for a monthly fee you can fly with the airline as much as you want. Is buffet-style air travel the wave of the future? JetBlue and Sun Country Airlines have both already tried offering all-you-can-fly passes, but so far no carrier has built its business model exclusively on a buffet plan. The idea isn't bad, but some scepticism is warranted. At $790 a month, Surf Air's flying plan will probably only appeal to business travellers who often go to the same places and rich Californians in long-distance relationships. Will that customer base allow Surf Air to make a profit? Maybe: 20m frequent flyers jetted between San Francisco and Los Angeles in 2011, according to the company's numbers. The airline plans to launch with service between Palo Alto, Monterey, Santa Barbara and Los Angeles, but it still needs to secure regulatory approval, according to a company press release. Frequent flyers make up a huge portion of the business-traveller population, and almost every airline relies on business travellers to get (and stay) in the black. There is surely some group of private-jet-sharing business travellers who might be attracted to an all-you-can-jet airline as a cheaper alternative. A lot will depend on how many flights and how much convenience Surf Air can offer, and how quickly it can expand service. The company's promises certainly seem attractive: [Surf Air will offer] its members 30-second booking and cancellations, travel to and from uncongested regional airports, and an easy arrive-and-fly process with no hassle, no lines and no extra fees. It's easy to make promises, though. It's much harder to run a profitable airline. As Gulliver often notes, the American airline sector overall has never really made any money—in fact, total earnings over the entire history of the industry are minus $33 billion. That, of course, suggests that existing airlines might be doing it wrong. Maybe all-you-can-fly really is the way to go. It's at least worth a shot. I'll be eager to see what people think of the final product—assuming regulators give the go-ahead.

Worrying is good for you and reflects higher IQ

It evolved in humans along with intelligence to make them more adept at avoiding danger. A study of 42 people found the worst sufferers of a common anxiety disorder had a higher IQ than those whose symptoms were less severe. Scientists say their findings published in Frontiers in Evolutionary Neuroscience, suggest worrying has developed as a beneficial trait. Psychiatrist Professor Jeremy Coplan, of SUNY Downstate Medical Centre in New York, and colleagues found high intelligence and worry are linked with brain activity measured by the depletion of the nutrient choline in the white matter of the brain. He said: "While excessive worry is generally seen as a negative trait and high intelligence as a positive one, worry may cause our species to avoid dangerous situations, regardless of how remote a possibility they may be. "In essence, worry may make people 'take no chances,' and such people may have higher survival rates. Thus, like intelligence, worry may confer a benefit upon the species." The researchers made the discovery by monitoring activity in the brains of twenty six patients with generalized anxiety disorder (GAD) and eighteen healthy volunteers to assess the relationship between IQ, worry and the metabolism of choline. In the control group high IQ was associated with a lower degree of worry, but in those diagnosed with GAD it was linked with more. The correlation between IQ and worry was significant in both the GAD group and the healthy control group. But in the former it was positive and in the latter negative. Previous studies have indicated excessive worry tends to exist both in people with higher and lower intelligence, and less so in people of moderate intelligence. It has been suggested people with lower intelligence suffer more anxiety because they achieve less success in life. Worrying has also been shown to lessen the effect of depression by countering brain activity that heightens the condition.

Eating nuts can help stave off obesity, says study

 

Dieters often dismiss them because of their high fat content, but research suggests that snacking on nuts can help keep you slim. A study found that those who consumed varieties such as almonds, cashews and pistachios demonstrated a lower body weight, body mass index (BMI) and waist circumference compared to non-consumers. They were also at lower risk of developing heart disease, type 2 diabetes and metabolic syndrome. Experts are now recommending a daily intake of 1.5 ounces, or three tablespoons of nuts as part of a healthy diet. Lead researcher Carol O'Neil, from Louisiana State University, said: 'One of the more interesting findings was the fact that tree nut consumers had lower body weight, as well as lower body mass index (BMI) and waist circumference compared to non-consumers. 'The mean weight, BMI, and waist circumference were 4.19 pounds, 0.9kg/m2 and 0.83 inches lower in consumers than non-consumers, respectively.' In the study, published in the Journal of the American College of Nutrition, researchers compared risk factors for heart disease, type 2 diabetes and metabolic syndrome of nut consumers versus those who did not consume nuts.

Thursday 12 April 2012

London buses have been booked to carry a Christian advertising campaign expected to start next week, which asserts the power of therapy to change the sexual orientation of gay people.

Core Issues Trust's advert states: 'Not gay! Post-gay, ex-gay and proud. Get over it!'
Core Issues Trust's advert states: 'Not gay! Post-gay, ex-gay and proud. Get over it!' mimicking the style of Stonewall's: 'Some people are gay. Get over it' advertising campaign which has run recently.

The full length advert, which will appear on five different routes in the capital, is backed by the Core Issues Trust whose leader, Mike Davies, believes "homoerotic behaviour is sinful". His charity funds "reparative therapy" for gay Christians who believe that they have homosexual feelings but want to become straight. The campaign is also backed by Anglican Mainstream, an worldwide orthodox Anglican group whose supporters have equated homosexuality with alcoholism.

The advert will say: "Not gay! Post-gay, ex-gay and proud. Get over it!" Post-gay and ex-gay are terms used by Christians and some psychotherapists and psychiatrists to refer to homosexual people who have undergone spiritual or pastoral therapy and, according to an Anglican Mainstream definition, have "now left a homosexual lifestyle [and experienced] an increased emotional and sexual attraction to the opposite biological gender and possibly a reduction in or loss of same-sex attraction."

The buses are due to roll out on Monday morning on some of the most popular routes. They will be seen for two weeks travelling past St Paul's Cathedral, down Oxford Street, round Trafalgar Square and through Piccadilly Circus as well as across other parts of the capital.

The campaign is an explicit attempt to hit back at gay rights group Stonewall, which ran its own bus advert saying: "Some people are gay. Get over it." The Christian groups have used the same black, red and white colour scheme as Stonewall and accuses it of promoting the "false idea that there is indisputable scientific evidence that people are born gay".

The Rev Lynda Rose, a spokesperson for the UK branch of Anglican Mainstream said because her group adheres to scripture that all fornication outside marriage is prohibited, it believes that homosexuals are "not being fully the people God intended us to be".

It has sparked an angry response from gay rights campaigners.

The former Europe minister and gay ex-vicar, Chris Bryant MP, said the advert was cruel, particularly to teenagers struggling to come to terms with their sexuality, for promoting the idea that you could become "ex-gay".

"The emotional damage that is done to the individuals who try to suppress their sexuality, the women they marry and the children they might have is immeasurable," he said. "Most sane Christians believe that homosexuality is not a lifestyle or a choice but is a fact to be discovered or not. The pretence that homosexuality is something you can be weaned off in some way is a fundamental misunderstanding of the nature of creation."

Ben Summerskill, the chief executive of Stonewall, said the adverts were clearly homophobic and added: "The only reason some gay people might want to stop being gay is because of the prejudice of the people who are publishing the ad.

"The promotion of this voodoo therapy is hugely irresponsible given the damage that it appears to do to some people."

Attempts to "treat" or alter sexual orientation have been strongly condemned by leading medical organisations. The Royal College of Psychiatrists has warned that "so-called treatments of homosexuality create a setting in which prejudice and discrimination flourish" and concluded in 2010 that "there is no sound evidence that sexual orientation can be changed". The British Medical Association has also attacked "conversion therapy", a related field to reparation therapy, passing a motion asserting that it is "discredited and harmful to those 'treated' ".

Rose said therapies endorsed by Anglican Mainstream and Core Issues were not coercive and stressed that they are appropriate for people who want to change their sexual attractions, for example if they are married and are worried about the impact of a gay lifestyle on their children.

"Reparative therapy works to help men, who want to change their sexual orientation, naturally dissipate their homoerotic feelings and maximise their heterosexual potential," she said.

In a statement, Anglican Mainstream and Core Issues said Stonewall's slogan is "merely another attempt to close down the critical debate about being gay, and marriage 'equality' ". They accused Stonewall of riding roughshod over individuals who chose to "move out of homosexuality".

The statement continued: "Both organisations recognise the rights of individuals to identify as gay, and to live according to their own values. But by the same token, they believe individuals – such as married men and women unhappy with their homosexuality – should be supported in developing their heterosexual potential where this is the appropriate life choice for them … Current scientific research says there is no gay gene and that sexuality is far more fluid than has hitherto been thought."

Your Vagina Isn't Just Too Big, Too Floppy, and Too Hairy—It's Also Too Brown


Good news, ladies! Society has discovered another new thing that's wrong with you, which means another opportunity for you to make yourself more attractive for your man. Score! Turns out, the color of your vagina is gross and everyone hates it. So bleach that motherfucker. Bleach it right now! In this commercial for an Indian product called Clean and Dry Intimate Wash, a (very light-skinned) couple sits down for what would have been a peaceful cup of morning coffee—if the woman's disgusting brown vagina hadn't ruined everything! The dude can't even bring himself look at her. He can't look at his coffee either, because it only reminds him of his wife's dripping, coffee-brown hole! Fortunately, the quick-thinking woman takes a shower, scrubbing her swarthy snatch with Clean and Dry Intimate Wash ("Freshness + Fairness"). And poof! Her vadge comes out blinding white like a downy baby lamb (and NOT THE GROSS BLACK KIND) and her husband—whose penis, I can only assume, is literally a light saber—is all, "Hey, lady! Cancel them divorce papers and LET'S BONE." Needless to say, certain citizens are troubled by this product—which, in addition to just being fucking insane, brings up painful issues about the hierarchy of skin tone within the Indian community. As if it isn't bad enough that darker-skinned people are encouraged to stay out of the sun and invest in skin-bleaching products like Fair & Lovely, and that white actresses are being imported to play Indian people in Bollywood movies, now everyone has to be insecure about the fact that their vaginas happen to be the color that vaginas are??? Splendid! God, I was just saying the other day that my misogyny didn't have enough racism in it. So what are the pro-vadge-bleaching people thinking? Here's a hilarious explanation from a male ad exec: It is hard to deny that fairness creams often get social commentators and activists all worked up. What they should do is take a deep breath and think again. Lipstick is used to make your lips redder, fairness cream is used to make you fairer-so what's the problem? I don't think any Youngistani today thinks the British Raj/White man is superior to us Brown folk. That's all 1947 thinking! The only reason I can offer for why people like fairness, is this: if you have two beautiful girls, one of them fair and the other dark, you see the fair girl's features more clearly. This is because her complexion reflects more light. I found this amazing difference when I directed Kabir Bedi, who is very fair and had to wear dark makeup for Othello, the Black hero of the play. I found I had to have a special spotlight following Kabir around the stage because otherwise the audience could not see his expressions. See? It makes perfect sense. We just want our vaginas to reflect more light—is that so wrong? I mean, WHAT IF MY CAR BREAKS DOWN AT NIGHT AND I DON'T HAVE A REFLECTIVE ENOUGH VAGINA? Really, the ultimate one-vagina-to-rule-them-all would glow in the dark like one of those deep-sea fishes. I need my vagina to attract more krill so my husband will fuck me again! (My husband is a whale.) Basically the idea is to get as far away as possible from any color that vaginas actually come in. Because that's what's at the heart of this type of thinking—the perfect vagina would be something that's not a vagina at all.

Friday 6 April 2012

On the prowl for pills, the big man with the shiny black loafers and fancy pickup truck broke into houses on the high plains of Montana.

When startled homeowners came upon him, he muttered something about being in the wrong residence, so sorry. And they wondered: Could this intruder really be the former N.F.L. quarterback, the Heisman Trophy finalist, the local kid paid $14 million before he tossed a single ball into opposition hands?

Yes, it was Ryan Leaf, police and prosecutors say — everybody’s All-American, arrested twice in the last week for burglary, theft and drug possession. See the mug shot: a familiar pose by now. The authorities say he turned predator toward Great Falls, the town that nurtured him on the way up and took him back a decade later, after he became one of the biggest busts in professional football.

The next address for Leaf, now 35, is likely to be prison, for parole violation. In 2008, he’d been granted his freedom instead of jail after pleading guilty to eight felonies in Texas, another state where a fleet-footed man with a football can do no wrong.

Ryan Leaf was arrested on April 12 in Great Falls, Mont.Getty ImagesRyan Leaf was arrested on April 12 in Great Falls, Mont.

When not stewing in a Montana cell, Leaf’s been out promoting his insipid new book, “596 Switch,” named for the last play he was going to run in his losing 1998 Rose Bowl effort — if only he’d been given a few more ticks of the clock. Just one more chance. In public, he extolled the new man, rehabbed and reborn. “My story has a positive ending to a negative experience,” he told Steve Kelley of the Seattle Times.

I never believed a word of it.

What do you call a coach who steals prescription drugs from his players, as Leaf did while tutoring quarterbacks at Texas A&M during one of many second chances?

What do you call a hometown hero who steals from the neighbors and friends who idolized him?

What do you call a man who risks being shot dead in his tracks in a gun-happy state, just to get his hands on another bottle of oxycodone?

A junkie, of course. And Leaf is the kind of junkie who shows all the odious traits — the convincing lies, the please, baby, please, you-gotta-believe-me vows and, worst of all, the vanity of his “recovery.”

Unless someone invents a cure for the dopamine-deprived, addiction will always will be with us. More than 23 million Americans need treatment for drug and alcohol abuse, and barely 10 percent of those tortured souls get that opportunity. Leaf was given his full rehab, his freedom, his book contract, because, you know, he doesn’t look like a criminal.

But perhaps it’s time to lock up Leaf and let somebody who’s done jail time but can’t throw a football have a shot at redemption.

Ryan Leaf in August 1998.Ryan Leaf in August 1998.

We’re smarter about junk now than we were during the fruitless War on Drugs. At that battle’s peak, more than 20 years ago, moralists like the former drug czar William Bennett warned of society’s being overrun by crackheads. Well-off whites caught sniffing cocaine got sabbaticals in luxury spas. Poor people taking the same drug in different form went to prison.

Back then, it was about race and fear and ignorance. The crack epidemic leveled off, faded, as these things do. But the American gulag filled up, with nonviolent drug offenders’ accounting for nearly a fourth of all people in prison.

And then, a different kind of addict appeared: the celebrity junkie, without hoodie or a hint of menace. Chris Herren, a white basketball phenom, went from the Boston Celtics to scrounging around bus stations in the middle of the night looking for heroin. Rush Limbaugh admitted that he had a problem with pills.

(Even Limbaugh’s hero, Gov. Rick Perry of Texas, is a pill popper, according to a new book, “Inside the Circus,” by Mike Allen and Evan Thomas. The authors say Perry was on prescription pain meds — legal, and certainly no indication of addiction — while undergoing self-immolation in the presidential debates. A Perry spokesman has denied the story, but the authors have solid journalistic credentials, and one detail, Perry singing, “I’ve been working on the raiiiillllroad, all the live-long day” while relieving himself, rings true.)

Here’s my takeaway: Drug addicts are all alike in one sense, whether black or white, rich or poor, gifted or stupid, except some of them get more chances than others.

Leaf was pampered and insulated, and felt entitled from the get-go. Flush with cash after having been picked second over all in the 1998 NFL draft (Peyton Manning was first), Leaf returned to his alma mater, Washington State University, at homecoming. He shouted “I could own you!” to somebody in a bar. Classy.

To his credit, he now says he was a jerk for much of his life, calling himself “an egomaniac with a self-esteem problem,” an apt oxymoron.

But I’ve had enough, thank you, of fallen celebrities sharing stories of the road back. “I’m using the tools I’ve learned to move forward rather than backward & will B open 2 talking about the details in days 2 come,” Leaf said in a Twitter message last Saturday, just before the second arrest.

His message proves only one thing: that he doesn’t seem to have taken an English composition class during his days as B.M.O.C. In books, at the least, he might have learned something about life.

Food Can Be Addictive, Says Dr. Nora Volkow, Director of the National Institute on Drug Abuse


Can food really be as addictive as drugs? In an impassioned lecture at Rockefeller University on Wednesday, Dr. Nora Volkow, director of the National Institute on Drug Abuse, made the case that the answer is yes and that understanding the commonalities between food and drug addictions could offer insights into all types of compulsive behavior. Volkow began by acknowledging that the idea is controversial. “This is a concept that is rejected by many people,” she said. “It has polarized the [addictions] field.” Many experts dismiss food as an addictive substance because it doesn’t lead to most people behaving like addicts — compulsively seeking food despite negative consequences. So, the reasoning goes, food can’t be as addictive as a drug like crack cocaine. What that fails to recognize, however, is that crack cocaine itself isn’t as addictive as is commonly believed. “If you look at people who take drugs, the majority are not addicted,” Volkow said. Indeed, even for drugs like crack and heroin, fewer than 20% of users become addicted. In contrast, if you look at the proportion of people who are currently obese — some 34% of adults over 20 — it’s a significantly larger group. Add in those who are overweight, and fully two-thirds of Americans clearly have significant difficulties controlling their food intake. So, measured by the proportion of those who behave in health-risking ways with each substance, food could actually be considered several times more “addictive” than crack.

Eating Berries Could Guard Men Against Parkinson's

 

Eating strawberries, blueberries, blackcurrants and blackberries, which are rich in flavonoids, could reduce the risk of Parkinson's disease in men, finds a research. Men who ate the fruits along with other foods rich in flavonoids were found to be 40 percent less likely to develop the brain disease, Daily Mail reported Thursday. And those who ate berries at least once a week could cut their risk of developing the disease by a quarter compared with those who never ate them, the study by British and US experts has found. Flavonoids - also found in tea and red wine - are antioxidants which can offer protection against diseases like heart disease, some cancers and dementia. The research is the first large-scale study looking at the effect of flavonoids in protecting against Parkinson's disease. It causes tremors and muscular rigidity or stiffness, and affects all kinds of movement in the body. Xiang Gao of Harvard School of Public Health, one of the study leaders, said: "Given the other potential health effects of berry fruits, such as lowering risk of hypertension as reported in our previous studies, it is good to regularly add these fruits to your diet."

Fake drugs hard to spot amid 1,800 UK wholesalers

 

Stamping out trade in counterfeit drugs like Roche's Avastin is an uphill fight for regulators, whose task is complicated by the presence of thousands of small wholesalers across Europe. In Britain alone - the transit point for a second fake batch of the cancer drug uncovered in the U.S. market - there are around 1,800 licensed wholesalers, according to the Medicines and Healthcare products Regulatory Agency (MHRA). That is the second highest number of pharmaceutical middlemen in Europe after Germany, where there are more than 3,000 - simply too many to allow for proper supervision, according to drug manufacturers, who have long complained about the ease with which medicines are shipped across borders. "We are concerned that the MHRA doesn't have sufficient resources to inspect all the premises that have a wholesale dealer licence," said Malcolm West, a supply chain expert at the Association of the British Pharmaceutical Industry. Lack of regular inspections increases the risk of things going wrong, which is what happened in the latest case involving bogus vials shipped from Turkey via Britain. The fake drugs contained none of Avastin's active ingredient, bevacizumab. Two UK-based wholesalers - Richard's Pharma and River East Supplies - exported the fake versions of the injectable drug to the United States. The supplies were labelled as Altuzan, which is the Turkish brand name for Avastin, according to the MHRA. That pattern of trade from the Middle East through Europe to the U.S. mirrors what was seen when fake Avastin first hit the headlines in February, underscoring the vulnerability of the global medicine supply chain. The initial case also involved River East. Officials at Richard's Pharma and River East - both of which have UK licences allowing them to trade in "biological products" such as Avastin - did not respond to repeated telephone calls asking for comment. PARALLEL TRADE The vast majority of medicines dispensed in Britain come from big multinational wholesalers like Celesio and Alliance Boots, but the MHRA figures show there is also a long tail of such smaller companies. These independent firms typically buy products in one country and sell them in another at a higher price in a short-term arbitrage trade. This "parallel" trade is perfectly legal, under European laws protecting free movement of goods, and also helps keep prices down, according to the European Association of Euro-Pharmaceutical Companies, representing parallel traders. But the practice is still controversial. In Britain, a parliamentary committee has been investigating shortages of some medicines in the wake of complaints that supplies are being sucked out of the country by parallel trade. The final session of the inquiry was held last week. Exports from Britain have been encouraged by a weak pound, which makes the country a cheap place for middlemen to source medicines. A few years back, British prices were relatively high and, as a result, there were extensive parallel imports.

Thursday 5 April 2012

Addictive painkiller sales surge in new parts of U.S.


Sales of the two most popular prescription painkillers in the United States have exploded in new parts of the country, an Associated Press analysis shows, worrying experts who say the push to relieve patients' suffering is spawning an addiction epidemic. Drug Enforcement Administration figures show dramatic rises between 2000 and 2010 in the distribution of oxycodone, the key ingredient in OxyContin, Percocet and Percodan. Some places saw sales increase sixteenfold. Meanwhile, the distribution of hydrocodone, the key ingredient in Vicodin, Norco and Lortab, is rising in Appalachia, the original epicenter of the U.S. painkiller epidemic, as well as in the Midwest. The increases have coincided with a wave of overdose deaths, pharmacy robberies and other problems in New Mexico, Nevada, Utah, Florida and other states. Opioid pain relievers, the category that includes oxycodone and hydrocodone, caused 14,800 overdose deaths in 2008 alone, and the death toll is rising, the Centers for Disease Control and Prevention says. Across the U.S., pharmacies received and ultimately dispensed the equivalent of 69 tons of pure oxycodone and 42 tons of pure hydrocodone in 2010, the last year for which statistics are available. That's enough to give 40 5-mg Percocets and 24 5-mg Vicodins to every person in the United States. The DEA data records shipments from distributors to pharmacies, hospitals, practitioners and teaching institutions. The drugs are eventually dispensed and sold to patients, but the DEA does not keep track of how much individual patients receive. The increase is partly due to the aging U.S. population with pain issues and a greater willingness by doctors to treat pain, said Gregory Bunt, medical director at New York's Daytop Village chain of drug treatment clinics. Sales are also being driven by addiction, as users become physically dependent on painkillers and begin "doctor shopping" to keep the prescriptions coming, he said. "Prescription medications can provide enormous health and quality-of-life benefits to patients," Gil Kerlikowske, the U.S. drug czar, told Congress in March. "However, we all now recognize that these drugs can be just as dangerous and deadly as illicit substances when misused or abused." Opioids like hydrocodone and oxycodone can release intense feelings of well-being. Some abusers swallow the pills; others crush them, then smoke, snort or inject the powder. Unlike most street drugs, the problem has its roots in two disparate parts of the country -- Appalachia and affluent suburbs, said Pete Jackson, president of Advocates for the Reform of Prescription Opioids. "Now it's spreading from those two poles," Jackson said. A few areas that include military bases or Veterans Affairs hospitals have seen large increases in painkiller use because of soldier patients injured in the Middle East, law enforcement officials say. Experts worry painkiller sales are spreading quickly in areas where there are few clinics to treat people who get hooked, Bunt said. In Utica, New York, Patricia Reynolds has struggled to find treatment after becoming dependent on hydrocodone pills originally prescribed for a broken tailbone. The nearest clinics offering Suboxone, an anti-addiction drug, are an hour's drive away in Cooperstown or Syracuse. And those programs are full and are not accepting new patients, she said. "You can't have one clinic like that in the whole area," Reynolds said. "It's a really sad epidemic. I want people to start talking about it instead of pretending it's not a problem and hiding."

Wednesday 4 April 2012

Freedom near after years in hell but Schapelle Corby is too scared to hope


CONVICTED drug smuggler Schapelle Corby last night said she was "too scared to get my hopes up" after Indonesia's Justice and Human Rights Ministry recommended her jail sentence be slashed by 10 years - meaning she could be back in Australia within weeks. Her family is now anxiously awaiting a decision by Indonesian President Susilo Bambang Yudhoyono, who will have the final say on whether Corby is released. From her cell at Bali's Kerobokan prison, Corby last night said she was waiting for more information about the ministry's recommendation. Her sister Mercedes, who was visiting Schapelle when the news broke, said that if Dr Yudhoyono did agree to cut 10 years from Corby's sentence, she would be eligible to go home immediately. "She will have done eight years in October, plus she's had two years reduced in good behaviour, so that's 10 years," she said. "So if another 10 years is cut, she should be pretty much eligible for release immediately." Mercedes said, if released, her sister planned to head straight back to Australia to live with her mother Rosleigh in Queensland. Corby was jailed for 20 years in 2004 for attempting to smuggle 4.1kg of marijuana into Bali in a body board bag. The announcement of the major breakthrough in the former Gold Coast beautician's drug saga came as a "pleasant shock" to Corby and her family yesterday when The Daily Telegraph told them of the ministry's recommendation. Mercedes was at the prison having a small birthday celebration with Schapelle for their younger sister Mele, who had just turned 22. "Oh wow, have they recommended clemency? I hope this is true. I better make some calls," she said. A few hours later Mercedes said the family was "too nervous" to get their hopes up and would await the President's ruling before they celebrated. Corby first launched her bid for clemency two years ago, appealing for an early release on the grounds she was suffering from mental illness which could endanger her life. "She's on anti-psychotics to keep her stable, but she goes up and down," Mercedes said. A Justice Ministry official yesterday revealed the recommendation to slash Corby's sentence was based on humanitarian grounds: "Our office agreed with her clemency. We recommended granting it." Corby's lawyer Iskander Nawing described it as a "huge development" and a breakthrough. The recommendation also includes an approval for clemency from the director-general of prisons. Dr Yudhoyono's decision will be based on the recommendation from the Justice Ministry, as well as advice from the Attorney-General's Department, Foreign Ministry and National Narcotics Board. Print

Whitney Houston 'Powdery' substance in hotel bathroom

 

Drug paraphernalia and a white powdery substance were discovered in Whitney Houston's hotel room on the day she died, according to a coroner. The full report says the 48-year-old was found on 11 February lying face down in an overflowing hotel bathtub. Investigators said they recovered a rolled-up piece of paper, a small spoon and a portable mirror in the bathroom. The autopsy concluded that the singer had drowned due to the effects of cocaine use and heart disease. The report also indicated the singer had a perforated nose, a sign of long-term substance abuse. The 42-page document gave more details than an initial report released last month. Houston was found dead hours before she was due to attend a pre-Grammy party. One of the world's best known singers in the 1980s and 1990s, Houston had a long battle with drug addiction. Friends and family have said she appeared committed to a comeback, including a new film, during the time before her death.

Tuesday 3 April 2012

New info about statin safety affects millions


U.S. Food and Drug Administration issued new safety information about these cholesterol-lowering drugs that are prescribed to millions of Americans to lower the risk of heart disease. If you're among them, you should understand what the FDA's new guidance means for your health. "Before anyone gets too concerned, you should know that statins are so widely used because they have a long track record of safety and effectiveness," says Dr. Mark Taber, a cardiologist with SSM Heart Institute at St. Joseph Health Center. "All in all, statins have a very high benefit to risk ratio. The widespread use of the drugs, when indicated, probably accounts to a significant degree for the improvement in life expectancy in this country." The FDA called attention to the threat of liver damage as a rare side effect of statins and advised that regular liver enzyme testing is no longer considered useful in predicting or preventing liver injury. "Actually, in general they liberalized the follow up needed for liver function tests on patients taking statins, due to the very low incidence of true liver issues," Taber says. The main warnings related to a slightly higher incidence of developing diabetes while on statins, and a poorly substantiated claim that statins could result in cognitive impairment. Taber points out that cognitive problems, such as confusion or memory problems, were not documented in clinical studies, only by patient reports to the FDA website. "By stating these concerns, the FDA is raising awareness about the potential side effects of statins, but cardiologists already know that there are inherent risks, and we monitor patients appropriately to help ensure that side effects do not occur or are dealt with quickly," Taber notes. "If there is any evidence of a side effect that could be problematic, we can change the medication. But the fact remains that it's important to decrease risk of heart disease, and for many people statins are needed when diet and exercise alone don't result in acceptable cholesterol levels." Whenever a new prescription medication is started, you should look over the package insert to learn about potential side effects. Signs of liver damage, for instance, include fatigue, loss of appetite, right upper abdominal pain, dark urine and jaundice. Any of these symptoms should be reported to your doctor for evaluation. It is important to remember that you should not stop taking a medication without consulting your doctor first. Discontinuing use of a prescribed drug can be far more dangerous than the side effect you're worried about. "All the side effects listed by the FDA are rare, and the risk of heart attack is far more concerning," Taber says. "Some patients may need extra monitoring or may need to try more than one statin before we find the optimal choice, but in general statins are very well tolerated and don't cause problems for the people who take them." The advice above is universal when it comes to your health. Concerns should be discussed with your doctor, and decisions should always be made as part of a team approach to creating a healthy life.

Why don't GPS warn you that statins can harm your memory?


John Holliday had been on a higher 40mg dose of cholesterol pills for only a few weeks when he started to lose his concentration. ‘I’d be watching TV and suddenly find myself unable to follow the plot of a drama,’ says John, 52, a telecoms project manager who lives in Southend-on-Sea, Essex, with his wife Jill, 51, and their two children Adam, 20, and Emma, 16. ‘I’d have to read the same page of a book over and over because I couldn’t take any information in. ‘I’d always been known for my amazing memory — I was great on trivia and had total recall of events that happened 20 years ago, but suddenly I couldn’t remember things and my brain felt fuzzy.’ Just like up to seven million other people in Britain, John had been prescribed a statin to lower his blood cholesterol levels. The drugs are credited by the British Heart Foundation as contributing towards the dramatic 50 per cent fall in deaths from heart attacks in the past ten years. But while there is consensus that statins are lifesavers for people who have previously had a heart attack, concern is growing over their debilitating side-effects. They include muscle weakness, depression, sleep disturbance, sexual dysfunction, muscle pain and damage, gastro-intestinal problems, headaches, joint pains and nausea. Now, official bodies here and in the U.S. have ordered that the drugs must carry warnings for cognitive problems, too. Worryingly, it’s claimed GPs are failing to warn patients of the effect statins can have on the mind — meaning they may mistake them for signs of ageing or Alzheimer’s. ‘When I went back to my doctor after six weeks for a blood test, I told him how dreadful I was feeling,’ says John. ‘But he just said all drugs had side-effects and didn’t mention reducing the dose.’ It's claimed GPs are failing to warn patients of the effect statins can have on the mind - meaning they may mistake them for signs of ageing or Alzheimer's Things came to a head when a friend showed John an electrical circuit he’d built for his car. ‘I’d worked with circuits since I was 16 but it made no sense,’ he says. So John insisted on seeing his doctor again and repeated his concerns about his rapidly declining memory. This time the GP told him he could start on another type of statin when he felt well enough, and so John stopped taking the drugs immediately. ‘It took a few months, but gradually my memory returned and I’ve got my concentration back. I can’t say for sure statins caused these problems, but it seems like too much of a coincidence.’ Earlier this year, the Food and Drug Administration (FDA) in the U.S. ordered statins must carry warnings that some users have reported cognitive problems including memory loss, forgetfulness and confusion. This followed a decision by the UK’s Medicines Healthcare Regulatory Agency (MHRA) to add memory problems to the list of  possible statin side-effects in late 2009. The FDA said reports about the symptoms were from across all statin products and age groups. Those affected reported feeling fuzzy or unfocused in their thought process — though these were found to be rare and reversible. The FDA also warned, following U.S. research, that patients on statins had a small excess risk of developing Type 2 diabetes — but stressed that the benefits of taking a statin still outweigh this. The MHRA had 2,675 reports for adverse drug reactions connected with statins between 2007 and 2011. Officially, side-effects are rare —affecting only 1 per cent of people on the pills — but some doctors say they are under-reported. Dr Malcolm Kendrick, a GP and author of The Great Cholesterol Con, says he frequently sees patients suffering from mental confusion in his job in hospital intermediary care for the elderly. ‘Many of the patients I see will have been admitted to hospital after a fall or similar crisis,’ he says. ‘If they appear confused I’ll often advise taking them off statins to see if it has any effect — in my experience, about 10 to 15 per cent of people who appeared to have memory problems experienced an improvement in their memory symptoms after being taken off the drug. ‘I had one dramatic case where a lady was admitted to hospital on 40mg a day of simvastatin with such poor memory function her family asked me about power of attorney. 'I suggested taking her off statins and within a week her memory had returned to normal. She went home a fit and independent 83-year-old.’ Dr Kendrick says cholesterol is the main constituent of synapses (structures that allow signals to pass between brain cells and to create new memories) and is essential for brain function. ‘It is still not proven that statins have a significant effect on mortality — it has been calculated that a man who has had a heart attack who took a statin for five years would extend his life by only 14 days. 'Too many statins are being given to people at low risk. ‘Even in the highest risk group you need to treat 200 people a year with statins to delay just one death. 'One day the harm these drugs are doing is going to be obvious — the benefits are being over-hyped and the risks swept under the carpet.’ While Dr Kendrick’s controversial view is in the minority, one large review of 14 studies by the London School of Hygiene and Tropical Medicine, published by the highly respected Cochrane Library last year, concluded there was ‘little evidence’ cholesterol-lowering drugs protect people who are not at risk of heart disease. This review has been criticised by other doctors who say side-effects are rare and that there are still benefits even for people at lower risk who do not have established heart disease. These defenders of statins include Professor Colin Baigent of the Clinical Trial Service at Oxford University, who published research in 2010 showing statins reduced deaths from all causes by 10 per cent over five years. ‘There is relatively little evidence of cognitive impairment — what evidence there is all comes from observational studies.  ‘People read about side-effects and then put two and two together and blame the statins for their muscle pain or other health problems — it’s just not reliable evidence. ‘If you look at the best-quality randomised controlled trial where patients don’t know if they are taking a statin or placebo, there is no evidence of memory problems. 'Even the FDA says the risks of cognitive problems are very small and go away when statins are discontinued. ‘We’re in danger of forgetting just how effective these drugs are.’ Dr Dermot Neely of the charity Heart UK, and lead consultant at the Lipid and Metabolic Clinic at the Royal Victoria Infirmary in Newcastle, agrees side-effects with statins are rare. ‘I’ve been dealing with patients on statins since 1987 and I can count on the fingers of one hand the number whose memory symptoms turned out to be caused by statins.’ However, he said he often saw patients who had not been told about side-effects. ‘It’s important GPs are clear about the drugs statins can interact with, such as certain antibiotics, as this can get overlooked. ‘If a patient notices an adverse effect after starting statins, they should discuss this with their GP —but not stop their drugs suddenly because this can be dangerous.’ Sonya Porter, 73, decided to stop taking statins after her memory problems became so bad that she walked away from a cashpoint leaving her money behind. ‘I was permanently fuzzy-headed and just couldn’t seem to concentrate,’ says Sonya, a retired PA from Woking, Surrey. Then I started to get scared I might have Alzheimer’s. After reading about memory problems associated with statins, I thought it was at least a possibility. I decided to come off the pills to see if it made any difference. ‘I didn’t ask my GP, I just did it — I’d rather die of a heart attack than Alzheimer’s disease. Within a month I felt normal again and didn’t have any problems with memory. ‘I’m terrified that I could have been misdiagnosed with Alzheimer’s.’ John Holliday is also reluctant to go back on statins. ‘I wouldn’t rule it out completely — my latest test showed my cholesterol levels have gone up,’ he says. ‘But on balance, I’d rather take my chances with heart disease than feel as confused as that again. It’s all very well living slightly longer — but it’s about quality of life, too.’

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